In this expanded paperback edition of his New York Times bestseller, longevity expert Dan Buettner draws on his research from extraordinarily long-lived communities—Blue Zones—around the globe to highlight the lifestyle, diet, outlook, and stress-coping practices that will add years to your life and life to your years.A long healthy life is no accident. It begins with good genes, but it also depends on good habits. If you adopt the right lifestyle, experts say, chances are you may live up to a decade longer. So what's the formula for success? National Geographic Explorer Dan Buettner has lead teams of researchers across the globe to uncover the secrets of Blue Zones—geographic regions where high percentages of centenarians are enjoying remarkably long, full lives.The recipe for longevity, Buettner has found, is deeply intertwined with community, lifestyle, and spirituality. You won't find longevity in a bottle of diet pills or with hormone therapy. You'll find it by embracing a few simple but powerful habits, and by creating the right community around yourself. In The Blue Zone, Buettner has blended his lifestyle formula with the latest longevity research to inspire lasting behavioral change and add years to your life.

A NEW YORK TIMES BESTSELLER“Brilliant and enthralling.” —The Wall Street JournalA paradigm-shifting book from an acclaimed Harvard Medical School scientist and one of Time’s most influential people.It’s a seemingly undeniable truth that aging is inevitable. But what if everything we’ve been taught to believe about aging is wrong? What if we could choose our lifespan?In this groundbreaking book, Dr. David Sinclair, leading world authority on genetics and longevity, reveals a bold new theory for why we age. As he writes: “Aging is a disease, and that disease is treatable.”This eye-opening and provocative work takes us to the frontlines of research that is pushing the boundaries on our perceived scientific limitations, revealing incredible breakthroughs—many from Dr. David Sinclair’s own lab at Harvard—that demonstrate how we can slow down, or even reverse, aging. The key is activating newly discovered vitality genes, the descendants of an ancient genetic survival circuit that is both the cause of aging and the key to reversing it. Recent experiments in genetic reprogramming suggest that in the near future we may not just be able to feel younger, but actually become younger.Through a page-turning narrative, Dr. Sinclair invites you into the process of scientific discovery and reveals the emerging technologies and simple lifestyle changes—such as intermittent fasting, cold exposure, exercising with the right intensity, and eating less meat—that have been shown to help us live younger and healthier for longer. At once a roadmap for taking charge of our own health destiny and a bold new vision for the future of humankind, Lifespan will forever change the way we think about why we age and what we can do about it.

“A fascinating look at how scientists are working to help doctors treat the aging process itself, helping us all to lead longer, healthier lives.” —Sanjay Gupta, MDAging—not cancer, not heart disease—is the underlying cause of most human death and suffering. The same cascade of biological changes that renders us wrinkled and gray also opens the door to dementia and disease. We work furiously to conquer each individual disease, but we never think to ask: Is aging itself necessary? Nature tells us it is not: there are tortoises and salamanders who are spry into old age and whose risk of dying is the same no matter how old they are, a phenomenon known as “biological immortality.” In Ageless, Andrew Steelecharts the astounding progress science has made in recent years to secure the same for humans: to help us become old without getting frail, to live longer without ill health or disease.

Keep your brain young, healthy, and sharp with this science-driven guide to protecting your mind from decline by neurosurgeon and CNN chief medical correspondent Sanjay Gupta. Throughout our life, we look for ways to keep our mind sharp and effortlessly productive. Now, globetrotting neurosurgeon Dr. Sanjay Gupta offers insights from top scientists all over the world, whose cutting-edge research can help you heighten and protect brain function and maintain cognitive health at any age. Keep Sharp debunks common myths about aging and cognitive decline, explores whether there’s a “best” diet or exercise regimen for the brain, and explains whether it’s healthier to play video games that test memory and processing speed, or to engage in more social interaction. Discover what we can learn from “super-brained” people who are in their eighties and nineties with no signs of slowing down—and whether there are truly any benefits to drugs, supplements, and vitamins. Dr. Gupta also addresses brain disease, particularly Alzheimer’s, answers all your questions about the signs and symptoms, and shows how to ward against it and stay healthy while caring for a partner in cognitive decline. He likewise provides you with a personalized twelve-week program featuring practical strategies to strengthen your brain every day. Keep Sharp is the only owner’s manual you’ll need to keep your brain young and healthy regardless of your age!

Is death inevitable? Until now, the history of mankind has been marked by this fatal fact. Religions, borders and progress are born from an ancient fear of death, comfort from this fear man often found only in religious paradigms. But according to José Luis Cordeiro and David Wood, the incontrovertible fact of death is no longer an absolute certainty - science and technology are preparing to tear down the final frontier: that of immortality.This accessible book provides insight into recent exponential advances in artificial intelligence, tissue regeneration, stem cell treatment, organ printing, cryopreservation, and genetic therapies that, for the first time in human history, offer a realistic chance to solve the problem of the aging of the human body. In this book, Cordeiro and Wood not only present all the major developments, initiatives, and ideas for eternal life, they also show why there are a number of good arguments for seeing death for what it is: the last undefeated disease.Enter any drugstore or bookstore, and we confronted with a mountain of nonsense concerning the aging process. Society seems obsessed with aging. That is why The Death of Death is such a refreshing delight, able to cut through the hype and reveal a balanced, authoritative, and lucid discussion of this controversial topic. It summarizes the astonishing breakthroughs made recently in revealing how science may one day conquer the aging process.Michio Kaku, theoretical physicist and author of The God Equation: The Quest for a Theory of EverythingWe are entering a Fantastic Voyage into life extension, crossing different bridges that will take us to indefinite life spans. The Death of Death explains clearly how we might soon reach longevity escape velocity and live long enough to live forever.Ray Kurzweil, co-author of Fantastic Voyage: Live Long Enough to Live Forever and co-founder of Singularity UniversityThe Death of Death is a truly revolutionary book. This is a visionary book that confronts us with the terrible reality of aging, and its authors are friends and connoisseurs of the subject. I believe that the authoritative and exhaustive description of this crusade that José and David make in this excellent book will accelerate this process. Forward!Aubrey de Grey, founder of LEV (Longevity Escape Velocity) Foundation and co-author of Ending Aging

Timeless wisdom on growing old gracefully from one of ancient Rome's greatest philosophers\nWorried that old age will inevitably mean losing your libido, your health, and possibly your marbles too? Well, Cicero has some good news for you. In How to Grow Old, the great Roman orator and statesman eloquently describes how you can make the second half of life the best part of all―and why you might discover that reading and gardening are actually far more pleasurable than sex ever was.\nFilled with timeless wisdom and practical guidance, Cicero's brief, charming classic―written in 44 BC and originally titled On Old Age―has delighted and inspired readers, from Saint Augustine to Thomas Jefferson, for more than two thousand years. Presented here in a lively new translation with an informative new introduction and the original Latin on facing pages, the book directly addresses the greatest fears of growing older and persuasively argues why these worries are greatly exaggerated―or altogether mistaken.\nMontaigne said Cicero's book "gives one an appetite for growing old." The American founding father John Adams read it repeatedly in his later years. And today its lessons are more relevant than ever in a world obsessed with the futile pursuit of youth.

The roadmap for finding purpose, meaning, and success as we age, from bestselling author, Harvard professor, and the Atlantic's happiness columnist Arthur Brooks. Many of us assume that the more successful we are, the less susceptible we become to the sense of professional and social irrelevance that often accompanies aging. But the truth is, the greater our achievements and our attachment to them, the more we notice our decline, and the more painful it is when it occurs. What can we do, starting now, to make our older years a time of happiness, purpose, and yes, success? At the height of his career at the age of 50, Arthur Brooks embarked on a seven-year journey to discover how to transform his future from one of disappointment over waning abilities into an opportunity for progress. From Strength to Strength is the result, a practical roadmap for the rest of your life. Drawing on social science, philosophy, biography, theology, and eastern wisdom, as well as dozens of interviews with everyday men and women, Brooks shows us that true life success is well within our reach. By refocusing on certain priorities and habits that anyone can learn, such as deep wisdom, detachment from empty rewards, connection and service to others, and spiritual progress, we can set ourselves up for increased happiness. Read this book and you, too, can go from strength to strength.

INSTANT NEW YORK TIMES BESTSELLERA moving account of resilience, hope, fear and mortality, and how these things resonate in our lives, by actor and advocate Michael J. Fox.The entire world knows Michael J. Fox as Marty McFly, the teenage sidekick of Doc Brown in Back to the Future; as Alex P. Keaton in Family Ties; as Mike Flaherty in Spin City; and through numerous other movie roles and guest appearances on shows such as The Good Wife and Curb Your Enthusiasm. Diagnosed at age 29, Michael is equally engaged in Parkinson’s advocacy work, raising global awareness of the disease and helping find a cure through The Michael J. Fox Foundation for Parkinson’s Research, the world’s leading non-profit funder of PD science. His two previous bestselling memoirs, Lucky Man and Always Looking Up, dealt with how he came to terms with the illness, all the while exhibiting his iconic optimism. His new memoir reassesses this outlook, as events in the past decade presented additional challenges.In No Time Like the Future: An Optimist Considers Mortality, Michael shares personal stories and observations about illness and health, aging, the strength of family and friends, and how our perceptions about time affect the way we approach mortality. Thoughtful and moving, but with Fox’s trademark sense of humor, his book provides a vehicle for reflection about our lives, our loves, and our losses.Running through the narrative is the drama of the medical madness Fox recently experienced, that included his daily negotiations with the Parkinson’s disease he’s had since 1991, and a spinal cord issue that necessitated immediate surgery. His challenge to learn how to walk again, only to suffer a devastating fall, nearly caused him to ditch his trademark optimism and “get out of the lemonade business altogether.”Does he make it all of the way back? Read the book.

Not only accepting but celebrating getting old, this inspirational and illuminating work looks at the many facets of the aging process, from purposes and challenges to struggles and surprises.

It’s a seemingly undeniable truth that aging is inevitable. But what if everything we’ve been taught to believe about aging is wrong? What if we could choose our lifespan?In this groundbreaking book, Dr. David Sinclair, leading world authority on genetics and longevity, reveals a bold new theory for why we age. As he writes: “Aging is a disease, and that disease is treatable.”This book takes us to the frontlines of research many from Dr. David Sinclair’s own lab at Harvard—that demonstrate how we can slow down, or even reverse, aging. The key is activating newly discovered vitality genes, the descendants of an ancient genetic survival circuit that is both the cause of aging and the key to reversing it.

The internationally renowned, clinically tested, revolutionary diet program to lose weight, fight disease, and live a longer, healthier life.Can what you eat determine how long, and how well, you live? The clinically proven answer is yes, and The Longevity Diet is easier to follow than you'd think. The culmination of 25 years of research on aging, nutrition, and disease across the globe, this unique program lays out a simple solution to living to a healthy old age through nutrition. The key is combining the healthy everyday eating plan the book outlines, with the scientifically engineered fasting-mimicking diet, or FMD; the FMD, done just 3-4 times a year, does away with the misery and starvation most of us experience while fasting, allowing you to reap all the beneficial health effects of a restrictive diet, while avoiding negative stressors, like low energy and sleeplessness. Valter Longo, director of the Longevity Institute at USC and the Program on Longevity and Cancer at IFOM in Milan, designed the FMD after making a series of remarkable discoveries in mice, then in humans, indicating that specific diets can activate stem cells and promote regeneration and rejuvenation in multiple organs to significantly reduce risk for diabetes, cancer, Alzheimer’s, and heart disease. Longo’s simple pescatarian daily eating plan and the periodic fasting-mimicking techniques can both yield impressive results. Low in proteins and sugars and rich in healthy fats and plant-based foods, The Longevity Diet is proven to help you:• Lose weight and reduce abdominal fat• Extend your healthy lifespan with simple everyday changes• Prevent age-related muscle and bone loss• Build your resistance to diabetes, cardiovascular disease, Alzheimer's and cancerLongo’s healthy, life span-extending program is based on an easy-to-adopt pescatarian plan along with the fasting-mimicking diet no more than 4 times a year, just 5 days at a time. Including 30 easy recipes for an everyday diet based on Longo's five pillars of longevity, The Longevity Diet is the key to living a longer, healthier, more fulfilled life.

#1 NEW YORK TIMES BESTSELLER • OVER ONE MILLION COPIES SOLD • A groundbreaking manifesto on living better and longer that challenges the conventional medical thinking on aging and reveals a new approach to preventing chronic disease and extending long-term health, from a visionary physician and leading longevity expert“One of the most important books you’ll ever read.”—Steven D. Levitt, New York Times bestselling author of FreakonomicsAN ECONOMIST AND BLOOMBERG BEST BOOK OF THE YEARWouldn’t you like to live longer? And better? In this operating manual for longevity, Dr. Peter Attia draws on the latest science to deliver innovative nutritional interventions, techniques for optimizing exercise and sleep, and tools for addressing emotional and mental health.For all its successes, mainstream medicine has failed to make much progress against the diseases of aging that kill most people: heart disease, cancer, Alzheimer’s disease, and type 2 diabetes. Too often, it intervenes with treatments too late to help, prolonging lifespan at the expense of healthspan, or quality of life. Dr. Attia believes we must replace this outdated framework with a personalized, proactive strategy for longevity, one where we take action now, rather than waiting.This is not “biohacking,” it’s science: a well-founded strategic and tactical approach to extending lifespan while also improving our physical, cognitive, and emotional health. Dr. Attia’s aim is less to tell you what to do and more to help you learn how to think about long-term health, in order to create the best plan for you as an individual. In Outlive, readers will discover:• Why the cholesterol test at your annual physical doesn’t tell you enough about your actual risk of dying from a heart attack.• That you may already suffer from an extremely common yet underdiagnosed liver condition that could be a precursor to the chronic diseases of aging.• Why exercise is the most potent pro-longevity “drug”—and how to begin training for the “Centenarian Decathlon.”• Why you should forget about diets, and focus instead on nutritional biochemistry, using technology and data to personalize your eating pattern.• Why striving for physical health and longevity, but ignoring emotional health, could be the ultimate curse of all.Aging and longevity are far more malleable than we think; our fate is not set in stone. With the right roadmap, you can plot a different path for your life, one that lets you outlive your genes to make each decade better than the one before.

From the author of the New York Times bestseller The Plant Paradox comes a groundbreaking plan for living a long, healthy, happy life.From the moment we are born, our cells begin to age. But aging does not have to mean decline. World-renowned surgeon Dr. Steven Gundry has been treating mature patients for most of his career. He knows that everyone thinks they want to live forever, until they hit middle age and witness the suffering of their parents and even their peers. So how do we solve the paradox of wanting to live to a ripe old age—but enjoy the benefits of youth?\nThis groundbreaking book holds the answer. Working with thousands of patients, Dr. Gundry has discovered that the “diseases of aging” we most fear are not simply a function of age; rather, they are a byproduct of the way we have lived over the decades. In The Longevity Paradox, he maps out a new approach to aging well—one that is based on supporting the health of the “oldest” parts of us: the microorganisms that live within our bodies.\nOur gut bugs—the bacteria that make up the microbiome—largely determine our health over the years. From diseases like cancer and Alzheimer’s to common ailments like arthritis to our weight and the appearance of our skin, these bugs are in the driver’s seat, controlling our quality of life as we age.\nThe good news is, it’s never too late to support these microbes and give them what they need to help them—and you—thrive. In The Longevity Paradox, Dr. Gundry outlines a nutrition and lifestyle plan to support gut health and live well for decades to come. A progressive take on the new science of aging, The Longevity Paradox offers an action plan to prevent and reverse disease as well as simple hacks to help anyone look and feel younger and more vital.

NATIONAL BESTSELLER A smart, research-driven case for why optimism, kindness, and strong social networks will help us live to 100. From the day her daughter was born, science journalist Marta Zaraska fretted about what she and her family were eating. She fasted, considered adopting the keto diet, and ran a half-marathon. She bought goji berries and chia seeds and ate organic food. But then her research brought her to read countless scientific papers and to interview dozens of experts in various fields of study, including molecular biochemistry, epidemiology and neuroscience. What Marta discovered shattered her long-held beliefs about aging and longevity. A strong support network of family and friends, she learned, lowers mortality risk by about 45 percent, while exercise only lowers it by about 23 percent. Volunteering your free time lowers it by 22 percent or so, while certain health fads like turmeric haven't been shown to help at all. These revelations led Marta Zaraska to a simple conclusion: In addition to healthy nutrition and physical activity, deepening friendships, practicing empathy and contemplating your purpose in life can improve your lifespan. Through eleven chapters that take her around the world, from catching wild mice in the woods of central England to flower arranging with octogenarians in Japan, from laboratories to "hugging centres," Marta embarks on an absorbing, entertaining and insightful journey to determine the habits that will have the greatest impact on our longevity. Deeply researched and expertly reported, Growing Young will dramatically change the way you seek a longer, happier life.

“Finding Ultra blends Rich Roll’s story of superhuman personal transformation with an amazingly practical guide to plant-based living. It’s also an enlightened manifesto for anyone wanting to transform their life.”—Dan Buettner, National Geographic Fellow and New York Times bestselling author of the Blue Zones books“An incredible story of mental, emotional, and physical endurance.”—Michael Greger, MD, FACLM, New York Times bestselling author of How Not to DieOn the night before he was to turn forty, Rich Roll experienced a chilling glimpse of his future. Nearly fifty pounds overweight and unable to climb the stairs without stopping, he could see where his current sedentary life was taking him—and he woke up.Plunging into a new routine that prioritized a plant-based lifestyle and daily training, Rich morphed—in a matter of mere months—from out of shape, mid-life couch potato to endurance machine. Finding Ultra recounts Rich’s remarkable journey to the starting line of the elite Ultraman competition, which pits the world’s fittest humans in a 320-mile ordeal of swimming, biking, and running. And following that test, Rich conquered an even greater one: the EPIC5—five Ironman-distance triathlons, each on a different Hawaiian island, all completed in less than a week.One of Men’s Fitness Magazine’s “25 Fittest Men in the World,” Rich has become one of the most recognized advocates of plant-based living. In this newly revised and updated edition, he shares the practices, tools, and techniques he uses for optimal performance, longevity, and wellness, including diet and nutrition protocols. Rich reflects on the steps he took to shift his mindset and leverage deep reservoirs of untapped potential to achieve success beyond his wildest imagination, urging each of us to embark on our own journey of self-discovery.

The New York Times bestselling book coauthored by the Nobel Prize winner who discovered telomerase and telomeres' role in the aging process and the health psychologist who has done original research into how specific lifestyle and psychological habits can protect telomeres, slowing disease and improving life.Have you wondered why some sixty-year-olds look and feel like forty-year-olds and why some forty-year-olds look and feel like sixty-year-olds? While many factors contribute to aging and illness, Dr. Elizabeth Blackburn discovered a biological indicator called telomerase, the enzyme that replenishes telomeres, which protect our genetic heritage. Dr. Blackburn and Dr. Elissa Epel's research shows that the length and health of one's telomeres are a biological underpinning of the long-hypothesized mind-body connection. They and other scientists have found that changes we can make to our daily habits can protect our telomeres and increase our health spans (the number of years we remain healthy, active, and disease-free).The Telemere Effect reveals how Blackburn and Epel's findings, together with research from colleagues around the world, cumulatively show that sleep quality, exercise, aspects of diet, and even certain chemicals profoundly affect our telomeres, and that chronic stress, negative thoughts, strained relationships, and even the wrong neighborhoods can eat away at them.Drawing from this scientific body of knowledge, they share lists of foods and suggest amounts and types of exercise that are healthy for our telomeres, mind tricks you can use to protect yourself from stress, and information about how to protect your children against developing shorter telomeres, from pregnancy through adolescence. And they describe how we can improve our health spans at the community level, with neighborhoods characterized by trust, green spaces, and safe streets.The Telemere Effect will make you reassess how you live your life on a day-to-day basis. It is the first book to explain how we age at a cellular level and how we can make simple changes to keep our chromosomes and cells healthy, allowing us to stay disease-free longer and live more vital and meaningful lives.

** A New York Times Bestseller **\\nNAMED ONE OF THE BEST BOOKS OF THE YEAR BY: Time • The New Yorker • NPR • GQ • Elle • Vulture • Fortune • Boing Boing • The Irish Times • The New York Public Library • The Brooklyn Public Library\\n"A complex, smart and ambitious book that at first reads like a self-help manual, then blossoms into a wide-ranging political manifesto."—Jonah Engel Bromwich, The New York Times Book Review\\nOne of President Barack Obama's "Favorite Books of 2019"\nPorchlight's Personal Development & Human Behavior Book of the Year\\nIn a world where addictive technology is designed to buy and sell our attention, and our value is determined by our 24/7 data productivity, it can seem impossible to escape. But in this inspiring field guide to dropping out of the attention economy, artist and critic Jenny Odell shows us how we can still win back our lives.\\nOdell sees our attention as the most precious—and overdrawn—resource we have. And we must actively and continuously choose how we use it. We might not spend it on things that capitalism has deemed important … but once we can start paying a new kind of attention, she writes, we can undertake bolder forms of political action, reimagine humankind’s role in the environment, and arrive at more meaningful understandings of happiness and progress.\\nFar from the simple anti-technology screed, or the back-to-nature meditation we read so often, How to do Nothing is an action plan for thinking outside of capitalist narratives of efficiency and techno-determinism. Provocative, timely, and utterly persuasive, this book will change how you see your place in our world.

This is the ultimate manual for longevity.\\nFor all its successes, mainstream medicine has failed to make much progress against the diseases of ageing that kill most people: heart disease, cancer, Alzheimer's disease, and type 2 diabetes. Too often, it intervenes with treatments too late, prolonging lifespan at the expense of quality of life. Dr Peter Attia, the world's top longevity expert, believes we must replace this outdated framework with a personalised, proactive strategy for longevity.\\nThis isn't 'biohacking,' it's science: a well-founded strategic approach to extending lifespan while improving our physical, cognitive and emotional health, making each decade better than the one before. With Outlive's practical advice and roadmap, you can plot a different path for your life, one that lets you outlive your genes to make each decade better than the one before.

Wall Street Journal, USA Today, and Publishers Weekly bestsellerThe prospect of living to 200 years old isn’t science fiction anymore. A leader in the emerging field of longevity offers his perspective on what cutting-edge breakthroughs are on the horizon, as well as the practical steps we can take now to live healthily to 100 and beyond.In The Science and Technology of Growing Young, industry investor and insider Sergey Young demystifies the longevity landscape, cutting through the hype and showing readers what they can do now to live better for longer, and offering a look into the exciting possibilities that await us. By viewing aging as a condition that can be cured, we can dramatically revolutionize the field of longevity and make it accessible for everyone.Join Sergey as he gathers insights from world-leading health entrepreneurs, scientists, doctors, and inventors, providing a comprehensive look into the future of longevity in two horizons:• The Near Horizon of Longevity identifies the technological developments that will allow us to live to 150—some of which are already in use—from AI-based diagnostics to gene editing and organ regeneration.• The Far Horizon of Longevity offers a tour of the future of age reversal, and the exciting technologies that will allow us to live healthily to 200, from Internet of Bodies to digital avatars to AI-brain integration.In a bonus chapter, Sergey also showcases 10 longevity choices that we already know and can easily implement to live to 100, distilling the science behind diet, exercise, sleep, mental health, and our environments into attainable habits and lifestyle hacks that anyone can adopt to vastly improve their lives and workplaces.Combining practical advice with an incredible overview of the brave new world to come, The Science and Technology of Growing Young redefines what it means to be human and to grow young.

How do some people avoid the slowing down, deteriorating, and weakening that plagues many of their peers decades earlier? Are they just lucky? Or do they know something the rest of us don’t? Is it possible to grow older without getting sicker? What if you could look and feel fifty through your eighties and nineties?Founder of the Institute for Aging Research at the Albert Einstein College of Medicine and one of the leading pioneers of longevity research, Dr. Nir Barzilai’s life’s work is tackling the challenges of aging to delay and prevent the onset of all age-related diseases including “the big four”: diabetes, cancer, heart disease, and Alzheimer’s.One of Dr. Barzilai’s most fascinating studies features volunteers that include 750 SuperAgers―individuals who maintain active lives well into their nineties and even beyond―and, more importantly, who reached that ripe old age never having experienced cardiovascular disease, cancer, diabetes, or cognitive decline.In Age Later, Dr. Barzilai reveals the secrets his team has unlocked about SuperAgers and the scientific discoveries that show we can mimic some of their natural resistance to the aging process. This eye-opening and inspirational book will help you think of aging not as a certainty, but as a phenomenon―like many other diseases and misfortunes―that can be targeted, improved, and even cured.

The question of how and why organisms age has teased scientists for centuries. There are myriad competing theories, from the idea that aging is a simple wear and tear process, like the rusting of a car, to the belief that aging and death are genetically programmed and controlled. In fact, there is no clearly defined limit to life, and no single, predictable program playing itself out: different things are happening within and between tissues, and each system or organ accumulates damage at its own pace, according to the kind of insults imposed on it by daily living.Sometime before 2020, the number of people over sixty-five worldwide will, for the first time, be greater than the number of 0-4 year olds; and by 2050 there are likely to be 2.5 times as many older people in the world as toddlers. Sue Armstrong tells the story of society's quest to understand aging through the eyes of the scientists themselves, as well as through the "ordinary" people who exemplify the mysteries of ageing--from those who suffer from the premature aging condition, Hutchinson-Gilford syndrome, to people still running marathons in their 80s.Borrowed Time will investigate such mind-boggling experiments as transfusing young blood into old rodents, and research into transplanting the first human head, among many others. It will explore where science is taking us and what issues are being raised from a psychological, philosophical and ethical perspective, through interviews with, and profiles of, key scientists in the field and the people who represent interesting and important aspects of aging.

A revolutionary examination of why we age, what it means for our health, and how we just might be able to fight it.In Cracking the Aging Code, theoretical biologist Josh Mitteldorf and award-winning writer and ecological philosopher Dorion Sagan reveal that evolution and aging are even more complex and breathtaking than we originally thought. Using meticulous multidisciplinary science, as well as reviewing the history of our understanding about evolution, this book makes the case that aging is not something that “just happens,” nor is it the result of wear and tear or a genetic inevitability. Rather, aging has a fascinating evolutionary purpose: to stabilize populations and ecosystems, which are ever-threatened by cyclic swings that can lead to extinction.When a population grows too fast it can put itself at risk of a wholesale wipeout. Aging has evolved to help us adjust our growth in a sustainable fashion as well as prevent an ecological crisis from starvation, predation, pollution, or infection.This dynamic new understanding of aging is provocative, entertaining, and pioneering, and will challenge the way we understand aging, death, and just what makes us human.

Bestselling author, longevity expert, and National Geographic Explorer Dan Buettner reports on health, fitness, diet, and aging, drawing on his research from extraordinarily long-lived communities--Blue Zones--around the globe. Buettner has launched a major public health initiative to transform cities based on principles from this book, an updated and expanded edition of his bestselling classic on longevity. His prescriptions for lifestyle, nutrition, outlook, and stress-coping practices will add years to your life and life to your years.The latest Blue Zone is Ikaria, Greece, where strong, sweet wine, family, and a Mediterranean diet all play a role in longer life. Also new in this book is a reading group guide, designed for groups to read about, discuss, and implement many of the simple changes advocated for better health.A long, healthy life is no accident. It begins with good genes, but it also depends on good habits. If you adopt the right lifestyle, experts say, chances are you may live up to a decade longer. Buettner has led teams of researchers across the globe--from Costa Rica to Sardinia, Italy, to Okinawa, Japan and beyond--to uncover the secrets of Blue Zones. He found that the recipe for longevity is deeply intertwined with community, lifestyle, and spirituality. People live longer and healthier by embracing a few simple but powerful habits, and by creating the right community around themselves. In The Blue Zones, Second Edition, Buettner has blended his lifestyle formula with the latest longevity research to inspire lasting, behavioral change and add years to your life.Region by region, Buettner reveals the "secrets" of longevity through stories of his travels and interviews with some of the most remarkable--and happily long-living people on the planet. It's not coincidence that the way they eat, interact with each other, shed stress, heal themselves, avoid disease, and view their world yield them more good years of life. Buettner's easy to follow "best practices" and list of healthy lifestyle choices from the Blue Zones will empower readers to live longer, healthier, more fulfilling lives.

How can you lose dramatic weight, ease chronic conditions, and stay healthier longer? Flip the switch on your metabolism with intermittent fasting, protein cycling, and keto!Within each of us is an ancient mechanism that eliminates toxic materials, initiates fat burning, and protects cells from becoming dysfunctional—or turning cancerous. It’s called autophagy, and when it’s turned on, the complex operation not only can slow down the aging process, it can optimize biological function as a whole, helping to stave off all manner of diseases and affording us the healthy life spans we never thought possible. It’s the body’s ultimate switch to life.So how can we positively activate this switch? How frequently should we fast and for how long? Which foods dial up autophagy or, conversely, turn it down? How much exercise and what types are recommended? What’s the sweet spot between intermittent fasting, protein cycling, and ketogenic eating?Backed by a wealth of scientific data and featuring a gallery of guidelines to follow for lasting results, The Switch decodes the science of autophagy and teaches you how to control it and maximize its profound impact.

'Endlessly fascinating and full of surprises. Easily one of my books of the year' BILL BRYSONThe myth-busting science behind our modern attitudes to exercise: what our bodies really need, why it matters, and its effects on health and wellbeing.In industrialized nations, our sedentary lifestyles have contributed to skyrocketing rates of obesity and diseases like diabetes. A key remedy, we are told, is exercise - voluntary physical activity for the sake of health. However, most of us struggle to stay fit, and our attitudes to exercise are plagued by misconceptions, finger-pointing and anxiety.But, as Daniel Lieberman shows in Exercised, the first book of its kind by a leading scientific expert, we never evolved to exercise. We are hardwired for moderate exertion throughout each day, not triathlons or treadmills. Drawing on over a decade of high-level scientific research and eye-opening insights from evolutionary biology and anthropology, Lieberman explains precisely how exercise can promote health; debunks persistent myths about sitting, speed, strength and endurance; and points the way towards more enjoyable and physically active living in the modern world.'Myth-busting, illuminating, brilliant - Lieberman will completely change the way you think about your body' Professor ALICE ROBERTS, presenter of Our Incredible Human Journey

This new book by Jim Mellon and Al Chalabi is a layman's guide to longevity. It investigates the new technologies and explains how to benefit from the life extending technologies both personally and professionally. It helps readers unravel the science, offers ideas on potential investment and reveals the views of the key opinion leaders.

With a New AfterwordMust We Age?Nearly all scientists who study the biology of aging agree that we will someday be able to substantially slow down the aging process, extending our productive, youthful lives. Dr. Aubrey de Grey is perhaps the most bullish of all such researchers. As has been reported in media outlets ranging from 60 Minutes to The New York Times, Dr. de Grey believes that the key biomedical technology required to eliminate aging-derived debilitation and death entirely―technology that would not only slow but periodically reverse age-related physiological decay, leaving us biologically young into an indefinite future―is now within reach.In Ending Aging, Dr. de Grey and his research assistant Michael Rae describe the details of this biotechnology. They explain that the aging of the human body, just like the aging of man-made machines, results from an accumulation of various types of damage. As with man-made machines, this damage can periodically be repaired, leading to indefinite extension of the machine's fully functional lifetime, just as is routinely done with classic cars. We already know what types of damage accumulate in the human body, and we are moving rapidly toward the comprehensive development of technologies to remove that -damage. By demystifying aging and its postponement for the nonspecialist reader, de Grey and Rae systematically dismantle the fatalist presumption that aging will forever defeat the efforts of medical science.

One of the Best Health and Wellness Books of 2017 ― Sports IllustratedDeep Nutrition cuts through today’s culture of conflicting nutritional ideologies, showing how the habits of our ancestors can help us lead longer, healthier, more vital lives.Physician and biochemist Catherine Shanahan, M.D. examined diets around the world known to help people live longer, healthier lives―diets like the Mediterranean, Okinawa, and “Blue Zone”―and identified the four common nutritional habits, developed over millennia, that unfailingly produce strong, healthy, intelligent children, and active, vital elders, generation after generation. These four nutritional strategies―fresh food, fermented and sprouted foods, meat cooked on the bone, and organ meats―form the basis of what Dr. Cate calls “The Human Diet.”Rooted in her experience as an elite athlete who used traditional foods to cure her own debilitating injuries, and combining her research with the latest discoveries in the field of epigenetics, Dr. Cate shows how all calories are not created equal; food is information that directs our cellular growth. Our family history does not determine our destiny: what you eat and how you live can alter your DNA in ways that affect your health and the health of your future children.Deep Nutrition offers a prescriptive plan for how anyone can begin eating The Human Diet to:*Improve mood*Eliminate cravings and the need to snack*Boost fertility and have healthier children*Sharpen cognition and memory*Eliminate allergies and disease*Build stronger bones and joints*Get younger, smoother skin

INTERNATIONAL BESTSELLER • 2 MILLION+ COPIES SOLD WORLDWIDE“Workers looking for more fulfilling positions should start by identifying their ikigai.” ―Business Insider“One of the unintended—yet positive—consequences of the [pandemic] is that it is forcing people to reevaluate their jobs, careers, and lives. Use this time wisely, find your personal ikigai, and live your best life.” ―ForbesFind your ikigai (pronounced ee-key-guy) to live longer and bring more meaning and joy to all your days.“Only staying active will make you want to live a hundred years.” —Japanese proverbAccording to the Japanese, everyone has an ikigai—a reason for living. And according to the residents of the Japanese village with the world’s longest-living people, finding it is the key to a happier and longer life. Having a strong sense of ikigai—where what you love, what you’re good at, what you can get paid for, and what the world needs all overlap—means that each day is infused with meaning. It’s the reason we get up in the morning. It’s also the reason many Japanese never really retire (in fact there’s no word in Japanese that means retire in the sense it does in English): They remain active and work at what they enjoy, because they’ve found a real purpose in life—the happiness of always being busy.In researching this book, the authors interviewed the residents of the Japanese village with the highest percentage of 100-year-olds—one of the world’s Blue Zones. Ikigai reveals the secrets to their longevity and happiness: how they eat, how they move, how they work, how they foster collaboration and community, and—their best-kept secret—how they find the ikigai that brings satisfaction to their lives. And it provides practical tools to help you discover your own ikigai. Because who doesn’t want to find happiness in every day?

An examination of the ethical issues raised by the possibility of human life extension, including its desirability, unequal access, and the threat of overpopulation.Life extension—slowing or halting human aging—is now being taken seriously by many scientists. Although no techniques to slow human aging yet exist, researchers have successfully slowed aging in yeast, mice, and fruit flies, and have determined that humans share aging-related genes with these species. In New Methuselahs, John Davis offers a philosophical discussion of the ethical issues raised by the possibility of human life extension. Why consider these issues now, before human life extension is a reality? Davis points out that, even today, we are making policy and funding decisions about human life extension research that have ethical implications. With New Methuselahs, he provides a comprehensive guide to these issues, offering policy recommendations and a qualified defense of life extension.After an overview of the ethics and science of life extension, Davis considers such issues as the desirability of extended life; whether refusing extended life is a form of suicide; the Malthusian threat of overpopulation; equal access to life extension; and life extension and the right against harm. In the end, Davis sides neither with those who argue that there are no moral objections to life enhancement nor with those who argue that the moral objections are so strong that we should never develop it. Davis argues that life extension is, on balance, a good thing and that we should fund life extension research aggressively, and he proposes a feasible and just policy for preventing an overpopulation crisis.

When we eat may be as important as what we eat. Discover how to reset your body’s natural clock—from an award-winning circadian rhythm and aging researcher“A complete program to recalibrate your day/night activities, optimize sleep, lose weight, learn/work, and exercise.”—Valter Longo, PhD, internationally bestselling author of The Longevity DietMost people typically wake up, get hungry for meals, and doze off in bed around the same time every day. But if you’ve ever experienced jet lag or pulled an all-nighter, you know that this schedule can easily be thrown off kilter. For some people, that imbalance—difficulty sleeping at night, hunger at odd times, or sudden fatigue at noon—is a constant. Dr. Satchin Panda, one of the leading researchers on circadian rhythms, has a plan to reset your body clock.Beginning with an in-depth explanation of the circadian clock—why it’s important, how it works, and how to know it isn’t working—The Circadian Code outlines lifestyle changes to make to get back on track. It’s a concrete plan to enhance weight loss, improve sleep, optimize exercise, and manage technology so that it doesn’t interfere with your body’s natural rhythm. Dr. Panda’s life-changing methods show you the keys to avoiding and alleviating chronic ailments like diabetes, cancer, and dementia, as well as digestive conditions like acid reflux, heartburn, and irritable bowel disease.In short, knowing your circadian code might just be the secret to turning back the clock and slowing down the aging process.

One of America's top doctors reveals how AI will empower physicians and revolutionize patient care Medicine has become inhuman, to disastrous effect. The doctor-patient relationship--the heart of medicine--is broken: doctors are too distracted and overwhelmed to truly connect with their patients, and medical errors and misdiagnoses abound. In Deep Medicine, leading physician Eric Topol reveals how artificial intelligence can help. AI has the potential to transform everything doctors do, from notetaking and medical scans to diagnosis and treatment, greatly cutting down the cost of medicine and reducing human mortality. By freeing physicians from the tasks that interfere with human connection, AI will create space for the real healing that takes place between a doctor who can listen and a patient who needs to be heard. Innovative, provocative, and hopeful, Deep Medicine shows us how the awesome power of AI can make medicine better, for all the humans involved. Illustrations note: 46 Halftones, black & white 11 Tables, black & white

“An impressive overview of how regenerative medicine may reverse aging and reboot the brain.”—Anthony Atala, MD, Director, Wake Forest Institute for Regenerative MedicineReplacing Aging outlines how aging will soon be reversible as a result of the advances that are being made in regenerative medicine. The book explains the enormous complexity of aging and how the accumulation of myriad types of macromolecular damage in the body essentially precludes a pharmacological solution to the problem of aging. Nevertheless drugs remain the primary focus of the anti-aging field. Instead of drugs, a decisive way to erase all forms of age-related macromolecular damage at once would be by replacing old worn-out tissues with new young ones. As the book describes, an ability to replace all body parts seems more and more likely, if not inevitable. Regenerative medicine is developing increasingly functional lab-grown cells, tissues, and organs that are being transplanted into patients today to treat diseases or repair damage. With continued improvements, cells and organs could be used in a more comprehensive manner to replace all body parts and reset the aging clock to near zero. Even the brain can be progressively replaced at a cellular level over time without a loss of self-identity. Existing examples demonstrate that complex brain functions can if given enough time change their neural substrates. And new brain cells added to old brains can form remarkably normal connection patterns. These findings together suggest protocols for brain rejuvenation. Thus, this book heralds the day in the near future when, if we choose to, we will be able to live much longer and healthier lives as a result of replacements made possible by regenerative medicine.“The central point made by this book is one of those fulcrums of comprehension on which all important progress depends: obvious to those who understand it, yet incongruous to those who do not. Rejuvenation is damage repair, and replacement and repair are the same thing viewed at different scales. Hebert’s articulation of this principle is the best yet.”—Aubrey de Grey, VP of New Technology Discovery at AgeX, Chief Scientific Officer of the SENS Research Foundation“This is a scientist’s perspective on aging as a condition that can be treated. The ideas that seem most like science fiction, such as replacing parts of the brain, are actually edging toward reality.”—Jeanne Loring, PhD, Co-founder of Aspen Neuroscience, Director of the Center for Regenerative Medicine at the Scripps Research Institute“Highly provocative and a great overview of recent progress in regenerative medicine and how it may at some point be applied in the fight against aging.”—Nir Barzilai, MD, Scientific Director for AFAR, Founding Director for the Institute of Aging Research at the Albert Einstein College of Medicine